Out-standing national and iberoamerican scientists meet at our country’s first Prinergic workshop.

At 9:00 a.m this Friday, with a ceremony in the Abate Molina auditorium, took place the beginning of activities, which will extend up to Saturday morning. The main researcher of the CRCP and CARE, Dr. Juan Pablo Huidobro, who was this week at La Serena, in the Latin-American Pharmacology Society congress, entity that he presides, is the person in charge of the organization of this meeting.

Between the out-standing figures that will atend the meeting is Dr. Stanko Stojilkovic, of NIH from USA., who studies the molecular structure of the purinergyc receptors or ATP. The importance of his research lays in that these are involved in the blood vessels contraction and therefore, in cardiac pathologys so frequent as the arterial hypertension.

Also takes part Argentina and Brazil distinguished academicians as Dr. Eduardo Lazarowski and Dr. Benedito Machado, who research the mechanisms of ATP's liberation and Glutamate, molecules that intervene in the pulmonary function.

Besides, there will be topics approached like the study of the adenosine receptos of in the foetal vascular endothelium. These works have woken a particular interest, because it has been shown that when this coordination its not right, produces foetal damage as well as multiple patologys.

The Biological Sciences Faculty Dean, Dr. Rafael Vicuña and the Director of the Cellular Regulation and Pathology center, and of the Aging and Regeneration Center, Dr. Nibaldo Inestrosa, will perform the welcome speeches to the more than 40 attendees who registered to take part.

Seminars:

Neuromodulation and neuroprotection by adenosine A1 and A2A receptors - R. Cunha.

Adenosine A2A receptor oligomerization in the basal ganglia: a potential target in Parkinson’s disease - F. Ciruela

Adenosine receptors A2A y A3 as modulators of the sympathetic nerve terminal M.V. Donoso Mechanisms of nucleotide release from lung epithelial cells - Eduardo Lazarowski.

Structural and functional characterization of recombinant purinergic P2X receptors - Stanko Stojilkovic

ATP-induced responses in visceral sensory neurons and the characterization of the receptors involved. - J Alcayaga

Purinergic transmission in the carotid body. R. Varas Zinc increases long-term potentiation through P2X receptors in CA1 area of rat hippocampus - R. Lorca.

Reactive oxygen Species potentiates The P2X2a receptor activity through cys430: an intracellular redox sensing mechanism for a purinergic receptor - C. Coddou.

Are L-glutamate and ATP cotransmitters of the peripheral chemoreflex in the nucleus tractus solitarius? - Benedito Machado

Concerted Action of Pannexin 1/Connexin based Hemichannels and P2 Receptors in Diverse Biological Responses - M.A. Riquelme

A role for adenosine receptors in the protective function of Nucleoside transporters 2 (hENT2) in micro and macrovascular human fetal endothelium? - L. Sobrevia.

Purinergic signaling in pituitary cells - S. Stojilkovic

Participants:

Francisco Ciruela.
Control of striatal neurotransmission by adenosine receptors oligomerization.

Rodrigo Cunha.
Roles of purines in the control of synaptic plasticity and brain dysfunction.

Eduardo Lazarowski.
Regulation of airway functions by released nucleotides.

J. Pablo Huidobro-Toro.
P2Y1 receptor life cycle and membrane rafts; studies in human vascular smooth muscle cells.

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